JCLJoe Chan Lab

Publications

84 papers since 2014. Preprints are posted to bioRxiv on submission; processed data accompany every paper.

Selected publications

10 papers · click for synopsis
  1. 2022Science

    Lineage plasticity in prostate cancer depends on JAK/STAT inflammatory signaling.

    Joseph M. Chan*, Samir Zaidi*, Jillian R. Love, Manu Setty, Kristine M. Wadosky, Anuradha Gopalan, Zi-ning Choo, Sitara Persad, Jungmin Choi, Justin LaClair, Kayla E Lawrence, Ojasvi Chaudhary, Tianhao Xu, Ignas Masilionis, Irina Linkov, Shangqian Wang, Cindy Lee, Afsar Barlas, Michael J. Morris, Linas Mazutis, Ronan Chaligne, Yu Chen, David W. Goodrich, Wouter R. Karthaus, Dana Pe’er, Charles L Sawyers. Science, 377, 1180–1191 (2022).Plasticity can be quantified at single-cell level to gain insight into underlying machinery. This strategy identified FGFR and JAK/STAT inflammation as a driver of plasticity in prostate cancer with combined FGFR and JAK inhibition reversing early stages of plasticity and restoring androgen sensitivity, but only prior to full neuroendocrine transformation.
  2. 2021Cancer Cell

    Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancer.

    Joseph M Chan*, Alvaro Quintanal-Villalonga*, Vianne Ran Gao*, Yubin Xie*, Viola Allaj, Ojasvi Chaudhary, Ignas Masilionis, Jacklynn Egger, Andrew Chow, Thomas Walle, Marissa Mattar, Dig V K Yarlagadda, James L Wang, Fathema Uddin, Michael Offin, Metamia Ciampricotti, Besnik Qeriqi, Amber Bahr, Elisa de Stanchina, Umesh K Bhanot, W Victoria Lai, Matthew J Bott, David R Jones, Arvin Ruiz, Marina K Baine, Yanyun Li, Natasha Rekhtman, John T Poirier, Tal Nawy, Triparna Sen, Linas Mazutis, Travis J Hollmann, Dana Pe’er, Charles M Rudin. Cancer Cell 2021 Nov 8;39(11):1479-1496.e18. doi: 10.1016/j.ccell.2021.09.008.Our single-cell atlas of SCLC patient tumors identifies plasticity changes in the form of a mixed SCLC-A/N phenotype as well as discrete intratumoral switching between canonical subtypes. We found a recurrent, pro-metastatic PLCG2-high SCLC phenotype that predicts worse overall survival and is associated with a pro-fibrotic myeloid population that is enriched in SCLC vs lung adenocarcinoma.
  3. 2021bioRxiv

    Multilineage plasticity in prostate cancer through expansion of stem–like luminal epithelial cells with elevated inflammatory signaling.

    Samir Zaidi*, Jimmy L. Zhao*, Joseph Chan*, Martine P. Roudier, Kristine M. Wadosky, Anuradha Gopalan, Wouter R. Karthaus, Jungmin Choi, Kayla Lawrence, Ojasvi Chaudhary, Tianhao Xu, Ignas Masilionis, Linas Mazutis, Ronan Chaligne, Irina Linkov, Afsar Barlas, Achim Jungbluth, Natasha Rekhtman, Joachim Silber, Katia Manova–Todorova, Philip A. Watson, Lawrence D. True, Peter S. Nelson, Howard I. Scher, Dana E. Rathkopf, Michael J. Morris, Michael C. Haffner, David W. Goodrich, Dana Pe’er, Charles L. Sawyers. bioRxiv 2021 Nov 3. https://www.biorxiv.org/content/10.1101/2021.11.01.466599v1Our single-cell exploration of castrate-resistant prostate cancer (CRPC) in transgenic mice following RB1, TP53, and PTEN deletion identified multi-lineage infidelity through the switch from a stem-like luminal population to amphicrine, mesenchymal, and multiple neuroendocrine subtypes that show correspondence to neuroendocrine subtypes in small cell lung cancer.
  4. 2020Clinical Cancer Research

    Tumor analyses reveal squamous transformation and off-target alterations as early resistance mechanisms to first-line osimertinib in EGFR-mutant lung cancer.

    Adam J Schoenfeld*, Joseph M Chan*, Daisuke Kubota, Hiroki Sato, Hira Rizvi, Yahya Daneshbod, Jason C. Chang, Paul K. Paik, Michael Offin, Maria E. Arcila, Monika Ashok Davare, Ujwal Shinde, Dana Pe’er, Natasha Rekhtman, Mark G. Kris, Romel Somwar, Gregory J. Riely, Marc Ladanyi, Helena A Yu. Clinical Cancer Research, 01/2020: doi: 10.1158/1078-0432.CCR-19-3563. https://www.ncbi.nlm.nih.gov/pubmed/31911548/
  5. 2019Journal of Thoracic Oncology

    Concurrent RB1 and TP53 alterations define a subset of EGFR-mutant lung cancers at risk for histologic transformation and inferior clinical outcomes.

    Michael Offin*, Joseph M Chan*, Megan Tenet, Hira A. Rizvi, Ronglai Shen, Gregory J. Riely, Natasha Rekhtman, Yahya Daneshbod, Alvaro Quintanal-Villalonga, Alexander Penson, Matthew D. Hellmann, Maria E. Arcila, Marc Ladanyi, Dana Pe’er, Mark G. Kris, Charles M. Rudin, Helena A. Yu. Journal of Thoracic Oncology, 06/2019: 10.1016/j.jtho.2019.06.002. https://www.ncbi.nlm.nih.gov/pubmed/31228622/
  6. 2019Nature Reviews: Clinical Oncology

    Lineage plasticity in cancer: a shared pathway of therapeutic resistance.

    Alvaro Quintanal-Villalonga*, Joseph M. Chan*, Helena A. Yu, Dana Pe’er, Charles L. Sawyers, Triparna Sen, Charles M. Rudin. Nature Reviews: Clinical Oncology, 03/2020: DOI: 10.1038/s41571-020-0340-z. https://www.ncbi.nlm.nih.gov/pubmed/32152485/
  7. 2013PNAS

    Topology of viral evolution.

    Joseph M Chan, Gunnar Carlsson, Raul Rabadan. PNAS, 2013: 110(46), 18566-18571. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831954/We developed a method based on algebraic topology to model horizontal evolution in viruses and any form of evolution not captured by standard phylogenetics. This method is one of the earliest applications of topological data analysis in the biological sciences.
  8. 2013Nature Genetics

    The integrated landscape of driver genomic alterations in glioblastoma.

    Veronique Frattini*, Vladimir Trifonov*, Joseph Minhow Chan*, Angelica Castano, Marie Lia, …, Anna Lasorella, Raul Rabadan, Antonio Iavarone. Nature Genetics, 2013: 45(1141-1149). http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799953/
  9. 2012Science

    Transforming Fusions of FGFR and TACC Genes in Human Glioblastoma.

    Devendra Singh*, Joseph Minhow Chan*, Pietro Zoppoli*, Francesco Niola*, …, Anna Lasorella, Raul Rabadan, Antonio Iavarone. Science, 07/2012: 337(6099), 1231-1235. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677224/By developing a method to detect gene fusions in both next-generation whole exome and RNA sequencing, we identified FGFR-TACC fusions in glioblastoma, the first instance of this oncogenic fusion in any cancer type.
  10. 2010PLoS Comput Biol

    Network Analysis of Global Influenza Spread.

    Chan J, Holmes A, Rabadan R. PLoS Comput Biol, 2010: 6(11): e1001005. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987833/

All publications

2007 — 2026

A complete list of publications can be found at MyNCBI.

Original Publications

2026

  1. 01Jiang Q, Raghavan MS, Rodriguez AM, Lallo M, Tam CL, Hartner S, Forsyth B, Mahmoud A, Zincke F, Zhao H, Moorman A, Balkaran S, Luckett K, Pintar J, Romin Y, Chan E, Santella A, Mödl B, Shah F, Baali I, Kharas MG, de Stanchina E, Urganci N, Shia J, Pe’er D, Sanchez-Vega F, Koche R, Morris Q, Chan JM, Ganesh K. ZFP36L2 orchestrates stress-adaptive plasticity in regeneration and cancer. Nature. 2026 Sept 1.

2025

  1. 01Seo Y, Zhang S, Jang J, Ko KP, Kim KB, Huang Y, Kim DW, Kim B, Zou G, Zhang J, Jun S, Chu W, Kirk NA, Hwang YE, Ban YH, Dhar SS, Chan JM, Lee MG, Rudin CM, Park KS, Park J-I. Actin dysregulation induces neuroendocrine plasticity and immune evasion: a vulnerability of small cell lung cancer. Nat Commun (2025). PMID: 41353272.PubMed
  2. 02Ireland AS, Xie DA, Hawgood SB, Barbier MW, Zuo LY, Hanna BE, Lucas-Randolph S, Tyson DR, Witt BL, Govindan R, Dowlati A, Moser JC, Thomas A, Puri S, Rudin CM, Chan JM, Elliott A, Oliver TG. Basal cell of origin resolves neuroendocrine–tuft lineage plasticity in cancer. Nature (2025). https://doi.org/10.1038/s41586-025-09503-zDOI
  3. 03Catozzi A, Peiris Pagès M, Humphrey S, Revill M, Morgan D, Roebuck J, Chen Y, Davies-Williams B, Brennan K, Mukarram Hossain ASM, Makeev VJ, Satia K, Sfyri PP, Galvin M, Coles D, Lallo A, Pearce SP, Kerr A, Priest L, Foy V, Carter M, Caeser R, Chan JM, Rudin CM, Blackhall F, Frese KK, Dive C, Simpson KL. Functional characterization of the ATOH1 molecular subtype indicates a pro-metastatic role in small cell lung cancer. Cell Rep. 2025 May 27;44(5):115603. PMCID: PMC12116416.

2024

  1. 01Zaidi S, Park J, Chan JM, et al. Single-cell analysis of treatment-resistant prostate cancer: Implications of cell state changes for cell surface antigen-targeted therapies. Proc Natl Acad Sci U S A. 2024 Jul 9;121(28):e2322203121. doi: 10.1073/pnas.2322203121. PMCID: PMC11252802.DOI
  2. 02Finlay JB, …, Chan JM, Goldstein BJ, Oliver TG. Olfactory neuroblastoma mimics molecular heterogeneity and lineage trajectories of small-cell lung cancer. Cancer Cell. 2024 Jun 10;42(6):1086-1105.e13. doi: 10.1016/j.ccell.2024.05.003. PMCID: PMC11186085.DOI
  3. 03Nabet, …, Chan JM, … et al. Immune heterogeneity in small-cell lung cancer and vulnerability to immune checkpoint blockade. Cancer Cell. 2024 Mar 11. PMID: 38366589.PubMed

2023

  1. 01Pai J, Hellmann M, Sauter J, Mattar M, Rizvi H, Woo H, Shah N, Nguyen E, Uddin F, Quintanal-Villalonga A, Chan J, Manoj P, Allaj V, Baine M, Bhanot U, Jain M, Linkov I, Meng F, Brown D, Chaft J, Plodkowski A, Gigoux M, Won H, Sen T, Wells D, Donoghue M, de Stanchina E, Wolchok J, Loomis B, Merghoub T, Rudin C, Chow A, Satpathy A. Lineage tracing reveals clonal progenitors and long-term persistence of tumor-specific T cells during immune checkpoint blockade. Cancer Cell, 2023. https://doi.org/10.1016/j.ccell.2023.03.009.DOI
  2. 02Li D, Zhan Y, Wang N, Tang F, Lee CJ, Bayshtok G, Moore AR, Wong EWP, Pachai MR, Xie Y, Sher J, Zhao JL, Khudoynazarova M, Gopalan A, Chan J, Khurana E, Shepherd P, Navone NM, Chi P, Chen Y. ETV4 mediates dosage-dependent prostate tumor initiation and cooperates with p53 loss to generate prostate cancer. Sci Adv. 2023 Apr 5;9(14):eadc9446. doi: 10.1126/sciadv.adc9446. PubMed PMID: 37018402; PMCID: PMC10075989.DOI
  3. 03Chow A, Uddin F, Liu M, Dobrin A, Nabet B, Mangarin L, Lavin Y, Rizvi H, Tischfield S, Quintanal-Villalonga A, Chan J, Shah N, Allaj V, Manoj P, Mattar M, Meneses M, Landau R, Ward M, Kulick A, Kwong C, Wierzbicki M, Yavner J, Egger J, Chavan S, Farillas A, Holland A, Sridhar H, Ciampricotti M, Hirschhorn D, Guan X, Richards A, Heller G, Mansilla-Soto J, Sadelain M, Klebanoff C, Hellmann M, Sen T, de Stanchina E, Wolchok J, Merghoub T, Rudin C. The ectonucleotidase CD39 identifies tumor-reactive CD8+ T cells predictive of immune checkpoint blockade efficacy in human lung cancer. Immunity, 2023: 56, 93-106.e6. 10.1016/j.immuni.2022.12.001.DOI

2022

  1. 01Joseph M. Chan, Samir Zaidi, Jillian R. Love, Manu Setty, Kristine M. Wadosky, Anuradha Gopalan, Zi-ning Choo, Sitara Persad, Jungmin Choi, Justin LaClair, Kayla E Lawrence, Ojasvi Chaudhary, Tianhao Xu, Ignas Masilionis, Irina Linkov, Shangqian Wang, Cindy Lee, Afsar Barlas, Michael J. Morris, Linas Mazutis, Ronan Chaligne, Yu Chen, David W. Goodrich, Wouter R. Karthaus, Dana Pe’er, Charles L Sawyers. Lineage plasticity in prostate cancer depends on JAK/STAT inflammatory signaling. Science, 2022.
  2. 02Nguyen EM, Taniguchi H, Chan JM, Zhan YA, Chen X, Qiu J, de Stanchina E, Allaj V, Shah NS, Uddin F, Manoj P, Liu M, Cai SF, Levine R, Quintanal-Villalonga A, Sen T, Chow A, Rudin CM. Targeting Lysine-Specific Demethylase 1 Rescues Major Histocompatibility Complex Class I Antigen Presentation and Overcomes Programmed Death-Ligand 1 Blockade Resistance in SCLC. J Thorac Oncol, 2022.
  3. 03Taniguchi H, Caeser R, Chavan SS, Zhan YA, Chow A, Manoj P, Uddin F, Kitai H, Qu R, Hayatt O, Shah NS, Quintanal Villalonga A, Allaj V, Nguyen EM, Chan J, Michel AO, Mukae H, de Stanchina E, Rudin CM, Sen T. WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC. Cell Rep, 2022.
  4. 04Quintanal-Villalonga A, Taniguchi H, Hao Y, Chow A, Zhan YA, Chavan SS, Uddin F, Allaj V, Manoj P, Shah NS, Chan JM, Offin M, Ciampricotti M, Ray-Kirton J, Egger J, Bhanot U, Linkov I, Asher M, Roehrl MH, Qiu J, de Stanchina E, Hollmann TJ, Koche RP, Sen T, Poirier JT, Rudin CM. Inhibition of XPO1 Sensitizes Small Cell Lung Cancer to First- and Second-Line Chemotherapy. Cancer Res, 2022.

2021

  1. 01A Quintanal-Villalonga, H Taniguchi, YA Zhan, MM Hasan, SS Chavan, F Meng, F Uddin, P Manoj, M Donoghue, HH Won, JM Chan, M Ciampricotti, A Chow, M Offin, JC Chang, J Ray-Kirton, SE Tischfield, J Egger, UK Bhanot, I Linkov, M Asher, S Sinha, J Silber, CA Iacobuzio-Donahue, MH Roehrl, TJ Hollmann, HA Yu, J Qiu, E de Stanchina, MK Baine, N Rekhtman, JT Poirier, B Loomis, RP Koche, CM Rudin, T Sen. Multi-omic analysis of lung tumors defines pathways activated in neuroendocrine transformation. Cancer Discovery, 2021.
  2. 02Joseph M Chan, Alvaro Quintanal-Villalonga, Vianne Ran Gao, Yubin Xie, Viola Allaj, Ojasvi Chaudhary, Ignas Masilionis, Jacklynn Egger, Andrew Chow, Thomas Walle, Marissa Mattar, Dig V K Yarlagadda, James L Wang, Fathema Uddin, Michael Offin, Metamia Ciampricotti, Besnik Qeriqi, Amber Bahr, Elisa de Stanchina, Umesh K Bhanot, W Victoria Lai, Matthew J Bott, David R Jones, Arvin Ruiz, Marina K Baine, Yanyun Li, Natasha Rekhtman, John T Poirier, Tal Nawy, Triparna Sen, Linas Mazutis, Travis J Hollmann, Dana Pe’er, Charles M Rudin. Signatures of plasticity, metastasis, and immunosuppression in an atlas of human small cell lung cancer. Cancer Cell, 2021 Nov 8;39(11):1479-1496.e18. doi: 10.1016/j.ccell.2021.09.008. https://pubmed.ncbi.nlm.nih.gov/34653364/DOI
  3. 03Quintanal-Villalonga A, Taniguchi H, Zhan YA, Hasan MM, Chavan SS, Meng F, Uddin F, Allaj V, Manoj P, Shah NS, Chan JM, Ciampricotti M, Chow A, Offin M, Ray-Kirton J, Egger JD, Bhanot UK, Linkov I, Asher M, Roehrl MH, Ventura K, Qiu J, de Stanchina E, Chang JC, Rekhtman N, Houck-Loomis B, Koche RP, Yu HA, Sen T, Rudin CM. Comprehensive molecular characterization of lung tumors implicates AKT and MYC signaling in adenocarcinoma to squamous cell transdifferentiation. J Hematol Oncol, 2021.
  4. 04Samir Zaidi, Jimmy L. Zhao, Joseph Chan, Martine P. Roudier, Kristine M. Wadosky, Anuradha Gopalan, Wouter R. Karthaus, Jungmin Choi, Kayla Lawrence, Ojasvi Chaudhary, Tianhao Xu, Ignas Masilionis, Linas Mazutis, Ronan Chaligne, Irina Linkov, Afsar Barlas, Achim Jungbluth, Natasha Rekhtman, Joachim Silber, Katia Manova–Todorova, Philip A. Watson, Lawrence D. True, Peter S. Nelson, Howard I. Scher, Dana E. Rathkopf, Michael J. Morris, Michael C. Haffner, David W. Goodrich, Dana Pe’er, Charles L. Sawyers. Multilineage plasticity in prostate cancer through expansion of stem–like luminal epithelial cells with elevated inflammatory signaling. bioRxiv, 2021 Nov 3. https://www.biorxiv.org/content/10.1101/2021.11.01.466599v1Link
  5. 05A Chow, S Schad, MD Green, MD Hellmann, V Allaj, N Ceglia, G Zago, NS Shah, SK Sharma, M Mattar, J Chan, H Rizvi, H Zhong, C Liu, Y Bykov, D Zamarin, H Shi, S Budhu, C Wohlhieter, F Uddin, A Gupta, I Khodos, JJ Waninger, A Qin, GJ Markowitz, V Mittal, V Balachandran, JN Durham, DT Le, W Zou, SP Shah, A McPherson, K Panageas, JS Lewis, JS Perry, E de Stanchina, T Sen, JT Poirier, JD Wolchok, CM Rudin, T Merghoub. Tim-4+ cavity-resident macrophages impair anti-tumor CD8+ T cell immunity. Cancer Cell, 2021.

2020

  1. 01Alvaro Quintanal-Villalonga, Joseph M. Chan, Helena A. Yu, Dana Pe’er, Charles L. Sawyers, Triparna Sen, Charles M. Rudin. Lineage plasticity in cancer: a shared pathway of therapeutic resistance. Nature Reviews: Clinical Oncology, 03/2020: DOI: 10.1038/s41571-020-0340-z. https://www.ncbi.nlm.nih.gov/pubmed/32152485/DOI
  2. 02HTAN consortium. The Human Tumor Atlas Network: Charting tumor transitions across space and time at single-cell resolution. Cell. 2020.
  3. 03Adam J Schoenfeld, Joseph M Chan, Daisuke Kubota, Hiroki Sato, Hira Rizvi, Yahya Daneshbod, Jason C. Chang, Paul K. Paik, Michael Offin, Maria E. Arcila, Monika Ashok Davare, Ujwal Shinde, Dana Pe’er, Natasha Rekhtman, Mark G. Kris, Romel Somwar, Gregory J. Riely, Marc Ladanyi, Helena A Yu. Tumor analyses reveal squamous transformation and off-target alterations as early resistance mechanisms to first-line osimertinib in EGFR-mutant lung cancer. Clinical Cancer Research, 01/2020: doi: 10.1158/1078-0432.CCR-19-3563. https://www.ncbi.nlm.nih.gov/pubmed/31911548/DOI

2019

  1. 01Michael Offin, Joseph M Chan, Megan Tenet, Hira A. Rizvi, Ronglai Shen, Gregory J. Riely, Natasha Rekhtman, Yahya Daneshbod, Alvaro Quintanal-Villalonga, Alexander Penson, Matthew D. Hellmann, Maria E. Arcila, Marc Ladanyi, Dana Pe’er, Mark G. Kris, Charles M. Rudin, Helena A. Yu. Concurrent RB1 and TP53 alterations define a subset of EGFR-mutant lung cancers at risk for histologic transformation and inferior clinical outcomes. Journal of Thoracic Oncology, 06/2019: 10.1016/j.jtho.2019.06.002. https://www.ncbi.nlm.nih.gov/pubmed/31228622/DOI

2017

  1. 01B Badal, A Solovyov, S Di Cecilia, J Chan, L Chang, R Iqbal, I Aydin, G Rajan, C Chen, F abbate, K Arora, A Tanne, S Gruber, T Johnson, D Fullen, L Raskin, R Phelps, N Bhardwaj, E Bernstein, D Ting, G Brunner, E Schadt, B Greenbaum, J Celebi. Transcriptional dissection of melanoma identifies a high-risk subtype underlying TP53 family genes and epigenome deregulation. Journal of Clinical Investigation, 2017.

2016

  1. 01D Kennedy, JM Chan, D Kaw, A Ravindaran, S Ratnam, D Malhotra, J Shapiro. Use of Surface-Enhanced Laser Desorption/Ionization with Time of Flight (SELDI-TOF) of the Urine in the Assessment of Acute Kidney Injury (AKI). Marshall Journal of Medicine, 2016: Vol. 2: Iss. 2, Article 11.

2015

  1. 01K Emmett, J Chan, D Rosenbloom, R Rabadan. Applying Topological Principles to Genomic Analysis. Microbe, 2015.

2014

  1. 01H Khibanian, Z Carpenter, J Kugelman, J Chan, V Trifonov, E Nagle, T Warren, P Iversen, S Bavari, G Palacios, R Rabadan. Viral diversity and clonal evolution from unphased genomic data. BMC Genomics, 2014: 15 (Suppl 6), S17.
  2. 02D Llobet-Navas, R Rodriguez-Barrueco, V Castro, A Ugalde, P Sumazin, D Jacob-Sendler, B Demircan, M Castillo-Martin, P Putcha, N Marshall, P Villagrasa, J Chan, F Sanchez-Garcia, D Pe’er, R Rabadan, A Iavarone, C Cordon-Cardo, A Califano, C Lopez-Otin, E Ezhkova, J Silva. The miR-424 (322)/503 cluster orchestrates remodeling of the epithelium in the involuting mammary gland. Genes and Development, 2014: 28(7), 765-782.

2013

  1. 01Joseph M Chan, Gunnar Carlsson, Raul Rabadan. Topology of viral evolution. PNAS, 2013: 110(46), 18566-18571. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3831954/Link
  2. 02Veronique Frattini, Vladimir Trifonov, Joseph Minhow Chan, Angelica Castano, Marie Lia, …, Anna Lasorella, Raul Rabadan, Antonio Iavarone. The integrated landscape of driver genomic alterations in glioblastoma. Nature Genetics, 2013: 45(1141-1149). http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3799953/Link
  3. 03Chan JM and Rabadan R. Quantifying Pathogen Surveillance Using Temporal Genomic Data. mBio, 2013: 4(1):e00524-12. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3560527/Link

2012

  1. 01Devendra Singh, Joseph Minhow Chan, Pietro Zoppoli, Francesco Niola, …, Anna Lasorella, Raul Rabadan, Antonio Iavarone. Transforming Fusions of FGFR and TACC Genes in Human Glioblastoma. Science, 07/2012: 337(6099), 1231-1235. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3677224/Link
  2. 02S J Anthony, J A St Leger, K Pugliares, H S Ip, J M Chan, Z W Carpenter, I Navarrete-Macias, M Sanchez-Leon, JT Saliki, J Pedersen, W Karesh, P Daszak, R Rabadan, T Rowles, W I Lipkin. Emergence of fatal avian influenza in New England harbor seals. mBio, 01/2012: 3(4). http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419516/Link

2011

  1. 01Laura Pasqualucci, Vladimir Trifonov, Giulia Fabbri, Jing Ma, Davide Rossi, Annalisa Chiarenza, Victoria A Wells, Adina Grunn, Monica Messina, Oliver Elliot, Joseph Chan, Govind Bhagat, Amy Chadburn, Gianluca Gaidano, Charles G Mullighan, Raul Rabadan, Riccardo Dalla-Favera. Analysis of the Coding Genome of Diffuse Large B-Cell Lymphoma. Nature Genetics, 2011: 43(9), 830-837. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3297422/Link
  2. 02Grossmann V, Tiacci E, Holmes AB, Kohlmann A, Martelli M, Kern W, Spanhol-Rosseto A, Klein H, Dugas M, Schindela S, Trifonov V, Schnittger S, Haferlach C, Bassan R, Wells V, Spinelli O, Chan J, Rossi R, Baldoni S, de Carolis L, Goetze K, Serve H, Peceny R, Kreuzer K, Oruzio D, Specchia G, di Raimondo F, Fabbiano F, Sborgia M, Liso A, Farinelli L, Rambaldi A, Pasqualucci L, Rabadan R, Haferlach T, Falini B. Whole-exome sequencing identifies mutations of BCOR in acute myeloid leukemia with normal karyotype. Blood, 2011: 118(23), 6153-6163.
  3. 03Carlos Xavier Hernandez, Joseph Chan, Hossein Khiabanian, Raul Rabadan. Understanding the Origins of a Pandemic Virus. arXiv, 2011: 1104.4568. Columbia University Academic Commons, AC:P:9893. http://arxiv.org/abs/1104.4568Link

2010

  1. 01Chan J, Holmes A, Rabadan R. Network Analysis of Global Influenza Spread. PLoS Comput Biol, 2010: 6(11): e1001005. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2987833/Link

2007

  1. 01Laederach A, Chan JM, Schwartzman A, Willgohs E, Altman RB. Coplanar and Coaxial Orientations of RNA Bases and Helices. RNA, 05/2007: 13(5):643-50. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1852812/Link